Comprehensive clinical and epidemiological assessment of colonisation and infection due to carbapenemase-producing Enterobacteriaceae in Spain

The paper “Comprehensive clinical and epidemiological assessment of colonisation and infection due to carbapenemase-producing Enterobacteriaceae in Spain”, by Palacios-Baena et al, has been recently published in Journal of Infection. Most previous clinical studies con carbapenemase-producing Enterobacteriaceae (CEP) include only specific patients (e.g., bacteraemic episodes or ICU patients), and most data in outcome analysis were performed…

In vivo evolution of resistance of Pseudomonas aeruginosa strains isolated from patients admitted to an intensive care unit: mechanisms of resistance and antimicrobial exposure.   [JAC (2015) 70:3004-13]

This has been a collaborative study between two groups of REIPI (Hospital Clinic of Barcelona and University Hospital Son Espases, Palma de Mallorca) with the aim of investigating the relationship among the in vivo acquisition of antimicrobial resistance in Pseudomonas aeruginosa clinical isolates, the underlying molecular mechanisms and previous exposure to antipseudomonal agents. All patients…

Risk factors predicting early invasive pulmonary aspergillosis in kidney transplant recipients: results from a multinational case-control study.

  American Journal Transplantation 2016 (in press) Risk factors for invasive pulmonary aspergillosis (IPA) after kidney transplantation (KT) have been poorly explored. We performed a multinational case-control study that included 51 KT recipients diagnosed with early (first 180 post-transplant days) IPA in 19 institutions between 2000 and 2013. Controls recipients were matched (1:1 ratio) by…

Impact of the minimum inhibitory concentration of piperacillin-tazobactam on the outcome of patients with bacteraemia due to Enterobacteriaceae: the Bacteraemia-MIC project.

Mercedes Delgado-Valverde, Eva Torres, Adoración Valiente-Mendez, Benito Almirante, Silvia Gómez-Zorrilla, Núria Borrell, Juan E. Corzo, Mercedes Gurgui, Manuel Almela, Lara García-Álvarez, María Cruz Fontecoba-Sánchez, Luis Martínez-Martínez, Rafael Cantón, Julia Praena, Manuel Causse, Belén Gutiérrez-Gutiérrez, Jason A. Roberts, Andras Farkas, Álvaro Pascual, Jesús Rodríguez-Baño and the REIPI/GEIH-SEIMC BACTERAEMIA-MIC group. Antimicrob. Chemother.2015 Nov 3. doi:10.1093/jac/dkv362  [Epub ahead…

SESIÓN ACCIONES COMPLEMENTARIAS DE PROGRAMACIÓN CONJUNTA INTERNACIONAL – Conferencia Horizonte 2020: Oportunidades de Financiación en Investigación e Innovación

Estimado Investigador/a, El próximo 3 de noviembre se celebrará en el Instituto de Salud Carlos III (ISCIII) la conferencia Horizonte 2020: Oportunidades de Financiación en Investigación e Innovación en el ámbito de la Salud para el periodo 2016-2017. En el marco de dicho evento, se organizará una sesión simultánea sobre las Acciones Complementarias de Programación…

The first trial in high-risk hematological patients to compare the serial detection of serum galactomanan (GM) and Aspergillus DNA with the conventional approach solely based on the GM assay

Article published in Clinical Infectious Disease by the Members of the PCRAGA Study Group The main objective of PCRAGA Study Group is to compare the use of the PCR- based detection of Aspergillus DNA versus the standard technique of determination of Galactomannan Antigen (AGA) in serum, recommended by the EORTC guidelines, in high risk hematological…