«Bacteriophages, Toxin-Antitoxin systems: Targets to develop of new treatments against bacterial persister cells»

«Bacteriophages, Toxin-Antitoxin systems: Targets for developing new treatments against bacterial persister cells» Researchers from the Spanish Network of Research in Infectious Diseases (REIPI) from 6 hospitals: A Coruña Hospital-INIBIC (A Coruña), Macarena Hospital-IBIS (Sevilla), Virgen del Rocio Hospital-IBIS (Sevilla), Clinic Hospital-IS Global (Barcelona), Marques de Valdecilla-IFIMAV (Santander) and Reina Sofia Hospital-IMIBIC (Cordoba) worked in the…

Prof. Jesús Rodríguez-Baño, coordinator of the Spanish network for research in infectious diseases (REIPI), is the new president of the Executive Committee of The European Society of Clinical Microbiology and Infectious Diseases (ESCMID).

ESCMID is self-defined as a non-profit organization whose mission is to improve the diagnosis, treatment and prevention of infection-related diseases. This is achieved by promoting and supporting research, education, training, and good medical practice. Prof. Rodríguez-Baño, MD PhD, is specialist in Infectious Diseases at the Department of Infectious Diseases and Clinical Microbiology, Hospital Virgen Macarena,…

The use of a single antibiotic may be enough to treat mild infections caused by resistant bacteria. Researchers from the Spanish Network of Research in Infectious Diseases (REIPI) have demonstrated it.

The investigations have been developed in infections caused by a bacterium called Klebsiella pneumoniae, which can be multiresistant. Until now, it was recommended to treat these infections with a combination of antibiotics. The research has been carried out in the Spanish Network of Research in Infectious Diseases (REIPI) and has been coordinated by researchers from…

Optimisation of empirical antimicrobial therapy in patients with haematological malignancies and febrile neutropenia (How Long study): an open-label, randomised, controlled phase 4 trial. Lancet Haematol 2017

The optimal duration of empirical antibacterial therapy for febrile neutropenia without microbiological diagnosis in haematological patients is not well defined; the classical approach of continuing antimicrobial therapy until neutrophil recovery may prolong it unnecessarily. This study aimed to establish whether the discontinuation of antimicrobial therapy driven by a clinical approach regardless of neutrophil recovery would…

A Predictive Model of Mortality in Patients With Bloodstream Infections due to Carbapenemase-Producing Enterobacteriaceae

A predictive score for mortality in patients suffering a bloodstream infection due to carbapenemase-producing Enterobacteriaceae has been published in Mayo Clinic Proceedings with data from the international cohort of INCREMENT (REIPI/ESGBIS) project. The predictive model included the following variables: severe sepsis or shock at presentation, Pitt score, Charlson, source other than urinary or biliary tracts…