The urinary tract conditions of patients with Escherichia coli infection improve fosfomycin activity.

The steps by which E. coli strains harboring mutations related to fosfomycin resistance arise and spread during urinary tract infections (UTIs) are far from being understood. A study performed by several REIPI groups (Hospital Universitario Virgen del RocĂ­o, Hospital Universitario Virgen Macarena and Centro Nacional de BiotecnologĂ­a) evaluates the effects of the urinary tract conditions…